(comicgenesis link to the same strip here)
We get a lot of pokeweed where I live. If left alone, the things can grow to the size of trees, dripping with berries which are toxic to cats and dogs, so when I see poke, I pull it. This year there was a lot of poke, in fact every time I went outside I saw more poke poking through the dirt. I'd walk over to pet the cat, I'd see some poke growing under the hedge and pull it (the poke, not the hedge. I'm not that...er, nevermind). I would go outside to turn on the light and come back with handfuls of poke.
Poke inspired the one and only meme I created, and apparently I don't know anyone who appreciates the importance of tracking down and pulling all the poke because this went the opposite of viral.